Could tiny space fighters carry weapons capable of killing a massive space carrier?
Short answerYes; a small attacker can exploit a vulnerable point or deliver the right weapon at the right moment.
NotesA large hull is not automatically immune to a much smaller attacker. Science fiction often supplies a vulnerable system, while naval history offers cases in which a small vessel reached the right place and delivered a decisive weapon. The outcome depends on access, timing, target vulnerability, and weapon effect rather than a simple comparison of displacement. A lucky attack on the right vulnerable point can matter more than the difference in size.