A trimaran escort could create space for unmanned systems

Could trimaran or pentamaran designs return for future destroyers?

Yes, especially if multihull volume and the gaps between hulls support uncrewed systems and long-range presence missions.

A future large escort might combine a wave-piercing or tumblehome-looking form with multiple hulls. The attraction goes beyond appearance. Spaces between the hulls could support launching and recovering uncrewed surface or underwater vehicles. A visibly imposing design could also carry political weight during peacetime deployments.