What was the difference between the earlier smallpox inoculation method and Jenner's vaccination?
Short answerThe earlier method used smallpox itself and risked causing the disease; Jenner used the related cowpox virus instead.
NotesAn older method used actual smallpox material and carried the risk of causing the full disease. Its introduction to Western Europe from the Ottoman world is recalled, with the date left uncertain. Edward Jenner's later approach used the related cowpox virus, which caused a much less severe illness. The connection with cows also explains the origin of the word vaccination.