Royal Navy submarines in the Indian and Pacific oceans

Did Royal Navy submarines have useful operations in the Pacific as well as the Mediterranean?

Yes, though their late return meant American submarines had already taken many of the best opportunities.

Royal Navy submarines were active in the Indian Ocean and could also operate effectively in the Pacific. Their wartime deployment shifted as Britain redistributed scarce boats among theaters. By the time they returned in force, American submarines had already exploited many of the most favorable Pacific targets. The answer makes timing and theater allocation, rather than submarine quality, the main limit.