How would HMS Indefatigable fare against USS Constitution?

How would HMS Indefatigable fare in a fight with USS Constitution?

It would be a hard fight, but Indefatigable might win because of her slightly heavier structure and comparable guns, with the commanders likely deciding the outcome.

Indefatigable retained the thick timbers of a cut-down ship of the line, giving her a structural advantage over a purpose-built frigate. Her guns and Constitution's were close enough in effect that the contest would not resemble Victory overwhelming a frigate. Indefatigable may have held an edge, although command would be decisive. William Bainbridge was capable enough to make the American ship a dangerous opponent even in an unfavorable comparison. The comparison applies the earlier explanation of razees to a concrete counterfactual matchup.