Helicopters as an outer defense against drones

Could helicopters provide the second outermost layer of air defense against drones, and how effective would they be?

Theoretically yes, especially against small surface drones and some aerial drones; machine guns might achieve the same effect more cheaply.

Helicopters could theoretically provide an outer defensive layer against drones. Small surface drones, including boat-sized and torpedo-boat-sized craft, are particularly suitable targets, and some aerial drones could also be engaged. Conventional machine guns might be as effective as the proposed equipment while costing much less.