Destroyer guns firing antisubmarine projectiles

Can destroyer main-gun ASW shells hit deep-diving or periscope-depth submarines?

Potentially; the exchange describes depth-charge-like projectiles but gives no verified depth, range, or hit-probability figures.

Destroyer main-gun attacks on submarines at periscope depth or deeper are considered potentially possible. The relevant projectile is compared with a long-range antisubmarine mortar round or depth charge. The participants point to BAE's published material for details. No performance figures are given, and the passage leaves the usable depth and range unquantified.