The deadliest naval campaigns beyond the Atlantic

What was the deadliest Second World War naval campaign besides the Battle of the Atlantic?

The Arctic convoys, American submarine war against Japan, and Mediterranean convoys are all plausible answers, with little to separate them.

The Arctic convoys could count as part of the Battle of the Atlantic, and their losses make them an obvious candidate. The US submarine campaign that devastated Japanese shipping in the Pacific offers another answer. Mediterranean convoy battles provide a further sustained and costly naval contest. Below the Atlantic campaign, the alternatives were too destructive in different ways to choose one clear second place.