American carriers in a Wake Island relief battle

Could concentrated American carriers defeat the Japanese force off Wake Island and cover relief or evacuation?

Yes, but the result depends on first detection and first strike because both sides' early carriers were glass cannons.

Kimmel's planned concentration might have placed two carriers near Wake in time to intervene. A third would improve the odds but would not remove the central uncertainty. Early Pacific carriers had powerful strikes without the mature fighter direction and layered defenses developed later in the war. If the Americans found the Japanese first they could win, while a Japanese first strike could reverse the result just as decisively.